As a designer, Anastassiades creates work with an enduring quality by focusing on proportion, the honest use of materials, and the physical presence of an object. Positioned between fine art and design, his work aims to provoke dialogue, participation and interaction. Anastassiades launched his studio in 1994 followed by his eponymous brand in 2007. In the years since, the company has produced a desired and unique collection of lighting, furniture, and objects. This has led to many successful collaborations with brands such as Flos, Herman Miller, Molteni, B&B Italia, Cassina, Kettal and Svenskt Tenn. He has designed signature limited edition collections for Friedman Benda, Nilufar Gallery, Dansk Møbelkunst and Taka Ishii Gallery. His work is featured in permanent collections at the Museum of Modern Art in New York, the Art Institute of Chicago, the Victoria & Albert Museum, London, the MAK in Vienna, the Crafts Council in London and the FRAC Centre in Orleans, France.